Description

Ethyl 4-[3-(Azetidinomethyl)Phenyl]-4-Oxobutyrate is a high-purity organic building block featuring a unique molecular scaffold combining an azetidine ring with a phenyl ketone ester. This compound matters as a critical intermediate in modern pharmaceutical research and development, enabling the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile azetidine and ketone functional groups.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of novel active ingredients for crop protection.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring this specific heterocyclic-phenyl framework.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocycle chemistry.

Basic Information

Product Name	Ethyl 4-[3-(Azetidinomethyl)Phenyl]-4-Oxobutyrate
CAS No.	898772-45-7
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	Ethyl 4-oxo-4-[3-(azetidin-1-ylmethyl)phenyl]butanoate; 4-[3-(Azetidin-1-ylmethyl)phenyl]-4-oxobutanoic Acid Ethyl Ester; 3-(Azetidin-1-ylmethyl)benzoylacetic Acid Ethyl Ester; Butanoic acid, 4-oxo-4-[3-(1-azetidinylmethyl)phenyl]-, ethyl ester; Ethyl 3-(azetidin-1-ylmethyl)benzoylacetate; 898772-45-7
EINECS	Contact for details

Quality Control

Our Ethyl 4-[3-(Azetidinomethyl)Phenyl]-4-Oxobutyrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.