Description

2-Acetoxybenzyl 2-Chloro-3-Pyridyl Ketone is a high-value, synthetically versatile organic intermediate of significant importance in advanced chemical synthesis. Its molecular architecture, featuring both pyridyl and benzyl ester functionalities, makes it a critical building block for the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical sectors seeking to introduce specific chloropyridine and protected phenolic motifs into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chloropyridine moiety is a common bioactive component.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, specialty organic compounds for various industrial applications.
• Ligand and Catalyst Development: Potential use in creating novel ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	2-Acetoxybenzyl 2-Chloro-3-Pyridyl Ketone
CAS No.	898766-35-3
Molecular Formula	C15H12ClNO3
Molecular Weight	289.71 g/mol
Synonyms	2-(Acetyloxy)benzyl 2-chloropyridin-3-yl ketone; (2-Acetoxybenzyl)(2-chloro-3-pyridinyl)methanone; 2-Chloro-3-pyridyl 2-acetoxybenzyl ketone; 2-Acetoxybenzyl 2-chloro-3-pyridinyl ketone; Ketone, 2-acetoxybenzyl 2-chloro-3-pyridyl
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 2-Acetoxybenzyl 2-Chloro-3-Pyridyl Ketone is monitored through in-process controls and final release testing via advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.