Description

Ethyl 8-[3-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-8-Oxooctanoate is a high-purity, synthetic organic compound featuring a complex molecular architecture that combines ester and spirocyclic amine functionalities. This structure makes it a valuable and versatile advanced pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those targeting neurological or metabolic disorders.
• Chemical Research & Development: Used as a precursor for creating novel spirocyclic and heterocyclic compounds in medicinal chemistry programs.
• Protease Inhibitor Synthesis: Serves as a critical intermediate in the development pathway for certain classes of enzyme inhibitors.
• Ligand and Receptor Studies: Employed in the design and synthesis of molecules for biochemical assays and target validation studies.
• Fine Chemical Production: Integrated into GMP or non-GMP production batches for custom synthesis and contract manufacturing services.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	Ethyl 8-[3-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-8-Oxooctanoate
CAS No.	898762-68-0
Molecular Formula	C26H39NO5
Molecular Weight	445.60 g/mol
Synonyms	Ethyl 8-[3-[(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)methyl]phenyl]-8-oxooctanoate; 8-[3-[(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)methyl]phenyl]-8-oxooctanoic Acid Ethyl Ester; 898762-68-0; UNII-9F8N1Q4Q4F; AS-64139; SCHEMBL218077; CTK8G0375; MolPort-044-690-947
EINECS	Contact for details

Quality Control

Our Ethyl 8-[3-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-8-Oxooctanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.