Description

3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Trifluorobenzophenone is a sophisticated organic intermediate featuring a benzophenone core modified with a spirocyclic dioxa-aza moiety and a trifluoromethyl group. This unique molecular architecture makes it a valuable building block in advanced pharmaceutical and agrochemical research, particularly for the synthesis of complex molecules with targeted biological activity. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for complex ligands in asymmetric catalysis or as a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science Research: Potential building block for advanced organic materials, such as liquid crystals or photoactive polymers, due to its rigid, functionalized structure.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Trifluorobenzophenone
CAS No.	898762-03-3
Molecular Formula	C22H22F3NO3
Molecular Weight	405.41 g/mol
Synonyms	2-Trifluoromethyl-3'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone; 3'-(1,4-Dioxa-8-azaspiro[4.5]dec-8-ylmethyl)-2'-(trifluoromethyl)benzophenone; 2'-Trifluoromethyl-3'-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylmethyl)benzophenone; 898762-03-3; Benzophenone, 3'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.