Description

2-Chloro-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a sophisticated organic compound featuring a benzophenone core integrated with a spirocyclic ketal-protected amine moiety. This unique molecular architecture makes it a highly valuable intermediate for the synthesis of complex pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, where its specific functional groups serve as critical building blocks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Protease Inhibitor Development: Serves as a core scaffold or intermediate for compounds designed to inhibit specific enzymes.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein functions.
• Advanced Organic Synthesis: Employed in multi-step synthetic routes requiring protected amine and ketone functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	2-Chloro-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898761-99-4
Molecular Formula	C23H26ClNO3
Molecular Weight	399.91 g/mol
Synonyms	2-Chloro-3'-(8-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)benzophenone; 2-Chloro-3'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]benzophenone; 898761-99-4; Benzophenone, 2-chloro-3'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-; 2-Chloro-3'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 2-Chloro-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.