Description

2,3-Dimethyl-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated chemical scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing spirocyclic and benzophenone-based molecular libraries.
• Preclinical Development: Serves as a critical material for producing batches of novel compounds for pharmacological and toxicological studies.
• Process Chemistry: Employed in route scouting and optimization for scalable API manufacturing processes.
• Chemical Biology Probes: Potential use in the development of molecular probes due to its photophysical properties and modifiable structure.

Basic Information

Product Name	2,3-Dimethyl-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898761-81-4
Molecular Formula	C24H29NO3
Molecular Weight	379.49 g/mol
Synonyms	2,3-Dimethyl-3'-(8-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)benzophenone; 2,3-Dimethyl-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decanyl)Methyl]Benzophenone; 898761-81-4; Benzophenone, 2,3-dimethyl-3'-[8-(1,4-dioxa-8-azaspiro[4.5]decanyl)methyl]-; Spirocyclic Benzophenone Derivative; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-[(2,3-dimethyl[1,1'-biphenyl]-3'-yl)methyl]-
EINECS	Contact for details

Quality Control

Our 2,3-Dimethyl-3'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide materials suitable for preclinical and clinical-stage development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.