Description

2,4-Difluoro-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique benzophenone and spirocyclic motifs.
• Precursor for Complex Heterocycles: The 1,4-dioxa-8-azaspiro[4.5]decyl moiety makes it a valuable precursor for synthesizing more complex spirocyclic and heterocyclic compounds.
• Ligand and Receptor Probe Development: Potential use in creating specialized ligands for biochemical and pharmacological research.
• Fine Chemical and Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	2,4-Difluoro-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898758-43-5
Molecular Formula	C25H27F2NO3
Molecular Weight	427.49 g/mol
Synonyms	2,4-Difluoro-4'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone; 4'-[8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-2,4-difluorobenzophenone; 2,4-Difluoro-4'-(1,4-dioxa-8-azaspiro[4.5]decane-8-methyl)benzophenone; Benzophenone, 2,4-difluoro-4'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]-; CAS 898758-43-5
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.