Description

2,5-Dichloro-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. It is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries who require a reliable and consistent supply of this specialized intermediate.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, especially for neurological and psychiatric applications.
• Organic Synthesis Building Block: Utilized in research and development for constructing complex molecules with spirocyclic and benzophenone motifs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable synthetic routes for API manufacturing.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical production.

Basic Information

Item	Details
Product Name	2,5-Dichloro-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898758-34-4
Molecular Formula	C23H25Cl2NO3
Molecular Weight	434.36 g/mol
Synonyms	2,5-Dichloro-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]benzophenone; 2,5-Dichloro-4'-[(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]benzophenone; 898758-34-4; Benzophenone, 2,5-dichloro-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-; Spirocyclic Benzophenone Derivative
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.