Description

4-Bromo-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Fluorobenzophenone is a sophisticated, high-purity organic intermediate featuring a unique spirocyclic and benzophenone architecture. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo, fluoro, and protected amine functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or warhead component in the design of bifunctional molecules for targeted protein degradation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides or fungicides with enhanced activity and selectivity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific optical or electronic properties.
• Chemical Biology Probe Synthesis: Employed to create molecular tools for studying enzyme function and biological pathways.
• Academic & Institutional Research: Provides a valuable scaffold for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4-Bromo-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Fluorobenzophenone
CAS No.	898758-16-2
Molecular Formula	C25H27BrFNO3
Molecular Weight	488.40 g/mol
Synonyms	4-Bromo-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]-2-fluorobenzophenone; 2-Fluoro-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-4-bromobenzophenone; 898758-16-2; Benzophenone, 4-bromo-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-2-fluoro-; 4-Bromo-4'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-2-fluorobenzophenone
EINECS	Contact for details

Quality Control

Our 4-Bromo-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-2-Fluorobenzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.