Description

4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-3-Trifluoromethylbenzophenone is a sophisticated organic intermediate featuring a benzophenone core modified with a spirocyclic acetal-protected amine and a trifluoromethyl group. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of advanced crop protection agents, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or electronic properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry due to its reactive functional groups and photophysical potential.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-3-Trifluoromethylbenzophenone
CAS No.	898758-12-8
Molecular Formula	C22H22F3NO3
Molecular Weight	405.41 g/mol
Synonyms	3-Trifluoromethyl-4'-[8-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]benzophenone; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-[[4-(3-(trifluoromethyl)benzoyl)phenyl]methyl]-; 4'-(1,4-Dioxa-8-azaspiro[4.5]dec-8-ylmethyl)-3'-(trifluoromethyl)benzophenone; 898758-12-8; Benzophenone, 4'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all critical parameters are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary and opened only in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.