Description

3,5-Dimethyl-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of next-generation therapeutics, where precise chemical structure and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates targeting neurological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Synthesis: Serves as a crucial scaffold for constructing complex molecules in the final stages of Active Pharmaceutical Ingredient (API) manufacturing.
• Chemical Biology Probes: Utilized in the development of labeled compounds and probes for studying biological mechanisms and target engagement.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Item	Details
Product Name	3,5-Dimethyl-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898757-98-7
Molecular Formula	C24H29NO3
Molecular Weight	379.49 g/mol
Synonyms	3,5-Dimethyl-4'-(8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl)benzophenone; 4'-(8-(1,4-Dioxa-8-azaspiro[4.5]decyl)methyl)-3,5-dimethylbenzophenone; 898757-98-7; Benzophenone, 3,5-dimethyl-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-; Spiroketal-substituted benzophenone derivative; Pharmaceutical Intermediate 898757-98-7
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.