Description

2,4-Dimethyl-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in process development and scale-up of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those targeting neurological pathways.
• Research & Development (R&D): Used in medicinal chemistry for lead optimization and the discovery of new chemical entities with potential therapeutic benefits.
• Process Chemistry: Serves as a standardized building block for process development, route scouting, and kilogram-scale laboratory synthesis.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final structural framework of APIs, contributing specific functional groups necessary for biological activity.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	2,4-Dimethyl-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898757-90-9
Molecular Formula	C24H29NO3
Molecular Weight	379.50 g/mol
Synonyms	4'-(8-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)methyl)-2,4-dimethylbenzophenone; 2,4-Dimethyl-4'-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)benzophenone; Benzophenone, 2,4-dimethyl-4'-[8-(1,4-dioxa-8-azaspiro[4.5]decyl)methyl]-; 898757-90-9; 4'-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-2,4-dimethylbenzophenone
EINECS	Contact for details

Quality Control

Our 2,4-Dimethyl-4'-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.