Description

2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-4'-Trifluorobenzophenone is a high-value, multifunctional organic intermediate featuring a unique spirocyclic and benzophenone architecture. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where its structural complexity enables the introduction of specific functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and inhibitors for biochemical pathway studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-4'-Trifluorobenzophenone
CAS No.	898756-33-7
Molecular Formula	C22H22F3NO3
Molecular Weight	405.41 g/mol
Synonyms	4'-(Trifluoromethyl)-2-[(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]benzophenone; 2-[(8-Methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]-4'-(trifluoromethyl)benzophenone; 898756-33-7; Benzophenone, 2-[(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]-4'-(trifluoromethyl)-; Trifluorobenzophenone spirocyclic ketal amine derivative
EINECS	Contact for details

Quality Control

Our 2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]-4'-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.