Description

3',5'-Dimethyl-2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone is a high-purity, specialized organic intermediate featuring a benzophenone core functionalized with a spirocyclic acetal-protected amine moiety. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Advanced Material Synthesis: Used in the research and development of specialty polymers, liquid crystals, and organic electronic materials.
• Agrochemical Research: Serves as a building block for developing new active ingredients for crop protection products.
• Chemical Biology & Proteomics: Can be utilized as a photoreactive probe or linker due to its benzophenone group, which facilitates photo-crosslinking studies.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthetic chemistry.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in producing complex, non-commercial molecules for clients.

Basic Information

Product Name	3',5'-Dimethyl-2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone
CAS No.	898756-15-5
Molecular Formula	C24H29NO3
Molecular Weight	379.49 g/mol
Synonyms	2-[(8-Methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]-3',5'-dimethylbenzophenone; 3',5'-Dimethyl-2-[(8-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]benzophenone; Benzophenone, 3',5'-dimethyl-2-[(8-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]-; 898756-15-5; 3,5-Dimethyl-2-((8-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)benzophenone
EINECS	Contact for details

Quality Control

Our production of 3',5'-Dimethyl-2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Benzophenone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are available for every batch and provided with shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.