Description

Ethyl 4-[2-(Azetidinomethyl)Phenyl]-4-Oxobutyrate is a high-purity, advanced pharmaceutical intermediate characterized by its specific molecular architecture. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the global pharmaceutical and fine chemical industries engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Organic Synthesis Building Block: Utilized in research-scale and pilot-scale organic reactions to construct more complex heterocyclic or substituted aromatic systems.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Item	Details
Product Name	Ethyl 4-[2-(Azetidinomethyl)Phenyl]-4-Oxobutyrate
CAS No.	898755-53-8
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	Ethyl 4-oxo-4-[2-(azetidin-1-ylmethyl)phenyl]butanoate; 4-[2-(Azetidin-1-ylmethyl)phenyl]-4-oxobutanoic acid ethyl ester; Butanoic acid, 4-oxo-4-[2-(1-azetidinylmethyl)phenyl]-, ethyl ester; Ethyl 4-(2-(azetidin-1-ylmethyl)phenyl)-4-oxobutyrate; 898755-53-8; AZD1283 Intermediate; AZD-1283 Impurity
EINECS	Contact for details

Quality Control

Our Ethyl 4-[2-(Azetidinomethyl)Phenyl]-4-Oxobutyrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.