Description

Ethyl 4-(2,4-Difluorophenyl)-4-oxobutyrate is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its precise chemical structure, which serves as a critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), especially those containing difluorophenyl motifs.
• Agrochemical Research: Serves as a building block for creating new pesticides, herbicides, and fungicides with enhanced efficacy.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high structural specificity.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D labs for constructing complex molecular architectures via reactions at the ketone and ester functional groups.
• Material Science: Potential monomer or precursor for advanced polymeric materials with specific optical or electronic properties.

Basic Information

Product Name	Ethyl 4-(2,4-Difluorophenyl)-4-oxobutyrate
CAS No.	898753-06-5
Molecular Formula	C12H12F2O3
Molecular Weight	242.22 g/mol
Synonyms	Ethyl 4-oxo-4-(2,4-difluorophenyl)butanoate; 4-(2,4-Difluorophenyl)-4-oxobutanoic Acid Ethyl Ester; Butanoic acid, 4-oxo-4-(2,4-difluorophenyl)-, ethyl ester; Ethyl 4-(2,4-Difluorobenzoyl)acetate (common misnomer, structurally related); 898753-06-5; Ethyl γ-oxo-2,4-difluorobenzene butanoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2,4-Difluorophenyl)-4-oxobutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.