Description

Ethyl 5-(3-Fluoro-4-Methylphenyl)-5-Oxovalerate is a high-purity, fluorinated keto ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a ketone and an ester functional group on an aliphatic chain attached to a fluorinated aromatic ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored optical or electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in synthetic organic chemistry.
• Custom Synthesis Building Block: Provides a flexible starting point for contract manufacturing organizations (CMOs) to produce bespoke compounds for clients.

Basic Information

Product Name	Ethyl 5-(3-Fluoro-4-Methylphenyl)-5-Oxovalerate
CAS No.	898752-58-4
Molecular Formula	C14H17FO3
Molecular Weight	252.28 g/mol
Synonyms	5-Oxo-5-(3-fluoro-4-methylphenyl)pentanoic acid ethyl ester; Ethyl 5-oxo-5-(3-fluoro-p-tolyl)valerate; 3-Fluoro-4-methyl-γ-oxobenzenepentanoic acid ethyl ester; Ethyl 5-(3-fluoro-4-methylbenzoyl)valerate; 898752-58-4; AKOS005258213; FT-0773788; SCHEMBL21824027
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-(3-Fluoro-4-Methylphenyl)-5-Oxovalerate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.