Description

Ethyl 5-(3,5-Difluorophenyl)-5-Oxovalerate is a high-purity organic intermediate featuring a difluorophenyl ketone moiety and an ester functional group. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific fluorinated aromatic structures into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluorophenyl group enhances biological activity and environmental stability.
• Fluorinated Compound Research: Serves as a critical precursor in academic and industrial R&D for exploring structure-activity relationships (SAR) in fluorinated organic molecules.
• Fine Chemical Manufacturing: Employed in the synthesis of complex flavors, fragrances, and functional materials that require specific aromatic ketone esters.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in regulatory and analytical laboratories.

Basic Information

Product Name	Ethyl 5-(3,5-Difluorophenyl)-5-Oxovalerate
CAS No.	898752-37-9
Molecular Formula	C13H14F2O3
Molecular Weight	256.25 g/mol
Synonyms	Ethyl 5-(3,5-Difluorobenzoyl)valerate; 5-(3,5-Difluorophenyl)-5-oxopentanoic Acid Ethyl Ester; Ethyl 5-Oxo-5-(3,5-difluorophenyl)pentanoate; 3,5-Difluorophenyl 4-Carbethoxybutyl Ketone; Pentanoic acid, 5-(3,5-difluorophenyl)-5-oxo-, ethyl ester; Ethyl 5-(3,5-Difluorophenyl)-5-oxopentanoate; 898752-37-9; Ethyl 5-(3,5-Difluorobenzoyl)pentanoate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(3,5-Difluorophenyl)-5-Oxovalerate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.