Description

1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylic Acid is a high-purity heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and advanced materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides with novel modes of action.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylic Acid
CAS No.	898746-35-5
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	6-Carboxy-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-6-carboxylic acid; 6-Azacarboxyril-3-carboxylic acid; 7-Azaindole-3-carboxylic acid (common misnomer, related structure); Azaindolecarboxylic acid derivative; Pyrrolopyridine-6-carboxylic acid; 6-(Carboxy)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-6-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.