Description

3-(5-Methoxy-Pyridin-3-Yl)-Prop-2-Yn-1-Ol is a high-purity pyridine-based alkyne derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a methoxypyridine ring and a propargylic alcohol group, makes it an essential intermediate for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and liquid crystals due to its conjugated alkyne system.
• Chemical Biology Probes: Utilized in click chemistry applications and as a building block for fluorescent tags or molecular probes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3-(5-Methoxy-Pyridin-3-Yl)-Prop-2-Yn-1-Ol
CAS No.	898561-63-2
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	3-(5-Methoxypyridin-3-yl)prop-2-yn-1-ol; 5-Methoxy-3-(2-hydroxyethynyl)pyridine; 3-(5-Methoxy-3-pyridinyl)-2-propyn-1-ol; 3-(5-Methoxypyridin-3-yl)propiolic alcohol; 3-(5-Methoxy-3-pyridyl)prop-2-yn-1-ol; 3-(5-Methoxy-pyridin-3-yl)-propyn-1-ol; 898561-63-2
EINECS	Contact for details

Quality Control

Our 3-(5-Methoxy-Pyridin-3-Yl)-Prop-2-Yn-1-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.