Description

n-(3-Iodo-4-Methoxy-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine-based molecular structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new molecular entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in multi-step synthetic routes for complex, high-value APIs.
• Bioconjugation & Probe Synthesis: The iodine moiety makes it suitable for further functionalization, useful in creating molecular probes for diagnostic or biochemical research.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for cGMP production of clinical trial materials and commercial APIs.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in organic synthesis and drug discovery.

Basic Information

Product Name	n-(3-Iodo-4-Methoxy-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide
CAS No.	898561-62-1
Molecular Formula	C11H15IN2O2
Molecular Weight	334.16 g/mol
Synonyms	2,2-Dimethyl-N-(3-iodo-4-methoxypyridin-2-yl)propanamide; 2,2-Dimethyl-N-(3-iodo-4-methoxy-2-pyridinyl)propanamide; Propanamide, N-(3-iodo-4-methoxy-2-pyridinyl)-2,2-dimethyl-; 3-Iodo-4-methoxy-N-pivaloylpyridin-2-amine; Pivalamide, N-(3-iodo-4-methoxy-2-pyridyl)-; CAS 898561-62-1
EINECS	Contact for details

Quality Control

Our n-(3-Iodo-4-Methoxy-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.