Description

(1R,2S,5R)-(-)-Menthyl Azide is a chiral, non-racemic organic azide derivative of (-)-menthol. This compound matters as a versatile chiral building block and a key precursor for click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require the introduction of a chiral menthyl auxiliary or the synthesis of complex triazole-based molecules with high stereochemical control.

Application

• As a chiral auxiliary in asymmetric synthesis for the preparation of enantiomerically pure compounds.
• A key precursor for click chemistry applications, enabling the efficient synthesis of 1,2,3-triazole derivatives.
• Intermediate in the research and development of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• Building block for novel ligands and catalysts used in stereoselective transformations.
• Starting material for the synthesis of chiral ionic liquids or other functional materials.
• Use in academic and industrial R&D for exploring new synthetic methodologies involving azide chemistry.

Basic Information

Product Name	(1R,2S,5R)-(-)-Menthyl Azide
CAS No.	898543-46-9
Molecular Formula	C₁₀H₁₇N₃
Molecular Weight	179.26 g/mol
Synonyms	(-)-Menthyl Azide; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Azide; L-Menthyl Azide; (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Azide; Azidomenthane; Menthyl N₃
EINECS	Contact for details

Quality Control

Our (1R,2S,5R)-(-)-Menthyl Azide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee reproducible performance and supply reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its light-sensitive nature, handling should be performed under subdued light or in amber glass containers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.