Description

tert-Butyl 4-(5-Bromo-6-Methoxypyridin-2-yl)piperazine-1-carboxylate is a high-value, multi-functional chemical building block designed for advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, serving as a key intermediate in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as an intermediate in the development of new pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new synthetic routes to heterocyclic compounds.

Basic Information

Product Name	tert-Butyl 4-(5-Bromo-6-Methoxypyridin-2-yl)piperazine-1-carboxylate
CAS No.	898533-41-0
Molecular Formula	C15H22BrN3O3
Molecular Weight	372.26 g/mol
Synonyms	1-Boc-4-(5-bromo-6-methoxypyridin-2-yl)piperazine; tert-Butyl 4-(5-bromo-6-methoxy-2-pyridinyl)-1-piperazinecarboxylate; 5-Bromo-6-methoxy-2-(1-piperazinyl)pyridine 1-Boc derivative; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-5-bromo-6-methoxypyridine; BOC-4-(5-Bromo-6-Methoxy-2-Pyridyl)Piperazine; 898533-41-0; 5-Bromo-6-methoxy-2-piperazin-1-yl-pyridine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Bromo-6-Methoxypyridin-2-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.