Description

3-Pyrimidin-2-Ylphenyl Isocyanate is a specialized aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a reactive isocyanate group attached to a pyrimidine-substituted phenyl ring, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polyurethanes and polyurea coatings with enhanced thermal or chemical resistance.
• Material Science: Building block for creating advanced organic frameworks, liquid crystals, or functional polymers with tailored electronic properties.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new heterocyclic compounds and conducting structure-activity relationship (SAR) studies.
• Bioconjugation: Potential use in modifying biomolecules or surfaces via its reactive isocyanate group for diagnostic or sensor applications.

Basic Information

Product Name	3-Pyrimidin-2-Ylphenyl Isocyanate
CAS No.	898289-49-1
Molecular Formula	C11H7N3O
Molecular Weight	197.19 g/mol
Synonyms	2-(3-Isocyanatophenyl)pyrimidine; 3-(Pyrimidin-2-yl)phenyl isocyanate; 1-Isocyanato-3-(pyrimidin-2-yl)benzene; m-(2-Pyrimidyl)phenyl isocyanate; 3-Pyrimidin-2-yl-benzenisocyanat; 898289-49-1; 3-(2-Pyrimidinyl)phenyl isocyanate
EINECS	Contact for details

Quality Control

Our 3-Pyrimidin-2-Ylphenyl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.