Description

Methyl 2-Thiomorpholin-4-Ylisonicotinate is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique thiomorpholine and pyridine motifs.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular tools and probes for studying enzyme function and biological pathways.
• Ligand Development for Catalysis: Acts as a starting material for synthesizing novel ligands used in transition metal-catalyzed reactions.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers with specific electronic or binding properties.

Basic Information

Product Name	Methyl 2-Thiomorpholin-4-Ylisonicotinate
CAS No.	898289-26-4
Molecular Formula	C11H14N2O2S
Molecular Weight	238.31 g/mol
Synonyms	Methyl 2-(thiomorpholin-4-yl)isonicotinate; 4-Pyridinecarboxylic acid, 2-(4-thiomorpholinyl)-, methyl ester; Methyl 2-(1,4-thiazepan-4-yl)isonicotinate; 2-(Thiomorpholin-4-yl)isonicotinic acid methyl ester; Isonicotinic acid, 2-(thiomorpholino)-, methyl ester; Methyl 2-(thiomorpholino)isonicotinate; 898289-26-4
EINECS	Contact for details

Quality Control

Our Methyl 2-Thiomorpholin-4-Ylisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.