Description

4-(Hydroxymethyl)-2-(Thiomorpholin-4-Yl)Pyridine is a high-value heterocyclic building block featuring a pyridine core substituted with a hydroxymethyl group and a thiomorpholine moiety. This unique structure makes it a critical intermediate in modern pharmaceutical research and development, particularly for the synthesis of targeted small molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable functional groups.
• API Synthesis: Serves as a building block in the multi-step synthesis of complex active pharmaceutical ingredients.
• Ligand and Catalyst Development: Potential precursor for creating specialized ligands in coordination chemistry or organocatalysts.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	4-(Hydroxymethyl)-2-(Thiomorpholin-4-Yl)Pyridine
CAS No.	898289-25-3
Molecular Formula	C11H16N2OS
Molecular Weight	224.32 g/mol
Synonyms	2-(Thiomorpholin-4-yl)-4-pyridinemethanol; 4-(Hydroxymethyl)-2-thiomorpholinopyridine; 4-Pyridinemethanol, 2-(thiomorpholin-4-yl)-; 2-Thiomorpholin-4-yl-pyridin-4-yl-methanol; 898289-25-3; 4-(Hydroxymethyl)-2-(thiomorpholino)pyridine; 4-(Hydroxymethyl)-2-(4-thiomorpholinyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)-2-(Thiomorpholin-4-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.