Description

tert-Butyl n-[1-(Pyridin-2-Yl)Azetidin-3-Yl]Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine-pyridine scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas such as kinase inhibition and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting protein kinases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Employed in the process development and scale-up of new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	tert-Butyl n-[1-(Pyridin-2-Yl)Azetidin-3-Yl]Carbamate
CAS No.	898271-45-9
Molecular Formula	C13H19N3O2
Molecular Weight	249.31 g/mol
Synonyms	tert-Butyl (1-(pyridin-2-yl)azetidin-3-yl)carbamate; 1-(Pyridin-2-yl)azetidin-3-amine, N-Boc-protected; N-Boc-1-(2-pyridyl)azetidin-3-amine; Boc-Azetidine-Pyridine Intermediate; tert-Butyl [1-(2-pyridinyl)-3-azetidinyl]carbamate; 898271-45-9; (1-(Pyridin-2-yl)azetidin-3-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[1-(Pyridin-2-Yl)Azetidin-3-Yl]Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to prevent degradation. For long-term storage, consider storing under nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.