Description

1-n-Boc-3-(Aminoethyl)Azetidine is a high-purity, protected heterocyclic amine building block of significant value in advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, where the Boc (tert-butoxycarbonyl) group offers orthogonal protection for the secondary amine, enabling selective reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and oncology targets.
• Peptidomimetic Chemistry: Used to introduce constrained azetidine rings into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts in asymmetric synthesis.
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological activity screening.
• Agrochemical Research: Utilized as a building block in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Potential monomer or cross-linker in the development of specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1-n-Boc-3-(Aminoethyl)Azetidine
CAS No.	898271-20-0
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-Boc-3-(2-aminoethyl)azetidine; tert-Butyl 3-(2-aminoethyl)azetidine-1-carboxylate; 3-(2-Aminoethyl)azetidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(2-aminoethyl)azetidine; Azetidine, 3-(2-aminoethyl)-, 1-(1,1-dimethylethyl) ester; 898271-20-0; Boc-AEA; 3-(2-Aminoethyl)azetidine hydrochloride Boc-protected
EINECS	Contact for details

Quality Control

Our 1-n-Boc-3-(Aminoethyl)Azetidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.