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6-(2-Methoxy-2-Oxoethoxy)Pyridine-3-Boronic Acid CAS NO 897952-14-6


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CAS No.:897952-14-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(2-Methoxy-2-Oxoethoxy)Pyridine-3-Boronic Acid is a high-purity, functionalized pyridine boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected carboxylic acid moiety, enabling precise and complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in advanced materials science for creating functional polymers and ligands.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
  • Agrochemical Synthesis: Used in creating novel pesticides and herbicides with improved efficacy and selectivity.
  • Material Science Building Block: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
  • Ligand Synthesis: Serves as a starting material for preparing sophisticated ligands used in catalysis and metal complexation.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
  • Cross-Coupling Reactions: Primarily functions as a versatile boronic acid partner in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl linkages.

Basic Information

Product Name 6-(2-Methoxy-2-Oxoethoxy)Pyridine-3-Boronic Acid
CAS No. 897952-14-6
Molecular Formula C9H12BNO5
Molecular Weight 225.01 g/mol
Synonyms 3-Pyridineboronic acid, 6-(2-methoxy-2-oxoethoxy)-; (6-[(Methoxycarbonyl)methoxy]-3-pyridinyl)boronic acid; 2-Methoxy-2-oxoethyl 5-borono-3-pyridinyl ether; 5-Borono-3-pyridinyloxyacetic acid methyl ester; 6-(Methoxycarbonylmethoxy)pyridine-3-boronic acid; 6-(Carboxymethoxy)nicotin-3-ylboronic acid methyl ester
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Quality Control

Every batch of 6-(2-Methoxy-2-Oxoethoxy)Pyridine-3-Boronic Acid is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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