Description

5-Amino-2-Cyano-4-Methylpyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both amino and cyano substituents on a methylated pyridine core, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the pyridine scaffold is a common bioactive moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Dye and Pigment Industry: Acts as a building block for synthesizing specialized heterocyclic dyes and colorants.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	5-Amino-2-Cyano-4-Methylpyridine
CAS No.	897733-08-3
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	4-Methyl-5-aminopyridine-2-carbonitrile; 2-Cyano-4-methyl-5-aminopyridine; 5-Amino-4-methylpicolinonitrile; 4-Methyl-2-cyano-5-aminopyridine; 5-Amino-4-methyl-2-pyridinecarbonitrile; 5-Amino-2-cyano-4-picoline
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Cyano-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.