Description

(S)-5'-Chloro-1-(4-Chlorophenyl)-2'-((R)-1-(4-Chlorophenyl)-4-Oxo-3,3-Diphenylazetidin-2-Yloxy)-3,3-Diphenylspiro[Azetidine-2.3'-Indoline]-4-One is a sophisticated, high-value chiral spirocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex, multi-functional structure makes it an essential building block for constructing novel molecular architectures with high stereochemical control. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients and complex target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel, high-performance pesticides and herbicides requiring specific stereochemistry for optimal activity.
• Asymmetric Catalysis Research: Serves as a valuable ligand or substrate in the development and study of new asymmetric catalytic reactions.
• Complex Molecule Construction: Employed in academic and industrial R&D for the total synthesis of complex natural products and other challenging molecular targets.
• Material Science Research: Investigated as a potential monomer or building block for creating novel polymers with unique optical or structural properties.

Basic Information

Product Name	(S)-5'-Chloro-1-(4-Chlorophenyl)-2'-((R)-1-(4-Chlorophenyl)-4-Oxo-3,3-Diphenylazetidin-2-Yloxy)-3,3-Diphenylspiro[Azetidine-2.3'-Indoline]-4-One
CAS No.	896746-44-4
Molecular Formula	C46H31Cl3N2O3
Molecular Weight	766.11 g/mol
Synonyms	Spiro[azetidine-2,3'-indoline]-4-one, 5'-Chloro-1-(4-chlorophenyl)-2'-[(1R)-1-(4-chlorophenyl)-4-oxo-3,3-diphenyl-2-azetidinyl]oxy]-3,3-diphenyl-, (2S)-; (2S)-5'-Chloro-1-(4-chlorophenyl)-2'-{[(1R)-1-(4-chlorophenyl)-4-oxo-3,3-diphenylazetidin-2-yl]oxy}-3,3-diphenylspiro[azetidine-2,3'-indoline]-4-one; CAS 896746-44-4; Advanced Spirocyclic Azetidine Intermediate; Chiral Spirooxindole-Azetidine Hybrid.
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is produced under strict quality management systems. Our rigorous analytical protocols ensure identity, purity, and stereochemical integrity, typically utilizing HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), chiral excess, and impurity profiles is provided with each shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.