Description

3-Pyridinecarboxamide, 5-Hydroxy-n-Methyl- is a high-purity, specialized heterocyclic compound serving as a critical building block in advanced organic synthesis. Its unique pyridine-based structure with hydroxyl and methylamide substituents makes it a valuable intermediate for creating complex molecules with targeted biological or material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system or metabolic diseases.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in fine chemical manufacturing.
• Material Science: Acts as a monomer or functional additive in the development of advanced polymers, coatings, or electronic materials requiring specific molecular interactions.
• Biochemical Research: Employed as a standard or reference compound in analytical method development and biochemical pathway studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis for client projects.

Basic Information

Product Name	3-Pyridinecarboxamide, 5-Hydroxy-n-Methyl-
CAS No.	896423-15-7
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	5-Hydroxy-N-methylnicotinamide; N-Methyl-5-hydroxynicotinamide; 5-Hydroxy-1-methyl-3-pyridinecarboxamide; 5-Hydroxy-N-methyl-3-pyridinecarboxamide; 3-Carbamoyl-5-hydroxy-1-methylpyridinium (inner salt form); 5-Hydroxy-1-methylpyridine-3-carboxamide; 5-Hydroxy-N-methyl-3-picolinamide; 1-Methyl-5-oxo-1,5-dihydropyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxamide, 5-Hydroxy-n-Methyl- is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), related substances, residual solvents, and other critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for demanding global applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.