Description

3-Pyridinamine, 5-Fluoro-, Monohydrochloride is a high-purity organic salt, specifically a fluorinated pyridine derivative, that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic and heterocyclic structure.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	3-Pyridinamine, 5-Fluoro-, Monohydrochloride
CAS No.	896161-34-5
Molecular Formula	C5H6FN2•HCl
Molecular Weight	148.57 (Free base) / 185.03 (HCl salt)
Synonyms	5-Fluoro-3-pyridinamine hydrochloride; 5-Fluoro-3-aminopyridine hydrochloride; 3-Amino-5-fluoropyridine hydrochloride; 5-Fluoro-pyridin-3-ylamine hydrochloride; 5-Fluoro-3-pyridylamine HCl; 3-Pyridinamine, 5-fluoro-, hydrochloride (1:1); 5-Fluoropyridin-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinamine, 5-Fluoro-, Monohydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA). Our quality standards are designed to meet the rigorous demands of GMP (Good Manufacturing Practice) environments for pharmaceutical intermediates and comply with global regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.