Description

2-(Benzyloxy)-4-Iodopyridine is a versatile halogenated pyridine derivative, primarily utilized as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a benzyl-protected oxygen and an iodine atom, makes it a valuable building block for constructing complex molecules through cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and infectious diseases.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Used in the synthesis of organic ligands for catalysts and in the creation of advanced organic electronic materials.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, enabling efficient carbon-carbon bond formation.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and methodological research in universities and contract research organizations (CROs).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, dyes, and specialty chemicals.

Basic Information

Product Name	2-(Benzyloxy)-4-Iodopyridine
CAS No.	896155-81-0
Molecular Formula	C12H10INO
Molecular Weight	311.12 g/mol
Synonyms	4-Iodo-2-(phenylmethoxy)pyridine; 2-Benzyloxy-4-iodopyridine; 4-Iodo-2-benzyloxypyridine; 2-(Benzyloxy)-4-iodo-pyridine; Pyridine, 4-iodo-2-(phenylmethoxy)-; 896155-81-0; 2-(Benzyloxy)-4-iodopyridin
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-4-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.