Description

1-(2-Nitro-Benzyl)-Piperidine-3-Carboxylic Acid is a high-purity, synthetically valuable piperidine derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Building block for developing new active ingredients in crop protection and pest management formulations.
• Chemical Synthesis: Versatile scaffold for constructing piperidine-containing compounds in medicinal and combinatorial chemistry.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal complexation.
• Academic & Institutional R&D: Essential material for research in synthetic methodology and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	1-(2-Nitro-Benzyl)-Piperidine-3-Carboxylic Acid
CAS No.	896052-75-8
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	1-[(2-Nitrophenyl)methyl]piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[(2-nitrophenyl)methyl]-; 1-(2-Nitrobenzyl)nipecotic acid; 2-Nitrobenzyl nipecotate; Nipecotic acid, 1-(2-nitrobenzyl)-; 896052-75-8; 1-(2-Nitrobenzyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Nitro-Benzyl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.