Description

1-(4-tert-Butyl-Benzyl)-Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct piperidine-carboxylic acid structure. This compound matters as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. Pharmaceutical R&D teams and fine chemical manufacturers need it for developing next-generation therapeutic candidates, leveraging its unique scaffold to introduce specific pharmacophores.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting neurological receptors.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new APIs, especially in areas of CNS disorders and pain management.
• Chemical Biology & Medicinal Chemistry: Employed as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex, high-value organic molecules in contract research and manufacturing.
• Academic & Industrial Research: Utilized in universities and corporate R&D labs for investigating new synthetic pathways and bio-active molecules.

Basic Information

Product Name	1-(4-tert-Butyl-Benzyl)-Piperidine-3-Carboxylic Acid
CAS No.	896049-22-2
Molecular Formula	C18H27NO2
Molecular Weight	289.41 g/mol
Synonyms	1-[(4-tert-Butylphenyl)methyl]piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[(4-(1,1-dimethylethyl)phenyl)methyl]-; 1-(4-tert-Butylbenzyl)nipecotic acid; 896049-22-2; tert-Butylbenzyl nipecotate derivative; 1-(4-tert-Butyl-benzyl)-3-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-tert-Butyl-Benzyl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.