Description

4-(Benzyloxy)-5-Bromo-3-Methoxypicolinic Acid is a high-purity, functionalized picolinic acid derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, or plant growth regulators.
• Ligand and Catalyst Development: Precursor for creating specialized ligands used in catalysis or metal complexation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-(Benzyloxy)-5-Bromo-3-Methoxypicolinic Acid
CAS No.	895134-21-1
Molecular Formula	C14H12BrNO4
Molecular Weight	338.16 g/mol
Synonyms	5-Bromo-3-methoxy-4-(phenylmethoxy)pyridine-2-carboxylic acid; 4-(Benzyloxy)-5-bromo-3-methoxypyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-bromo-3-methoxy-4-(phenylmethoxy)-; 5-Bromo-4-(benzyloxy)-3-methoxypicolinic acid; 4-Benzyloxy-5-bromo-3-methoxypicolinic acid
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-5-Bromo-3-Methoxypicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.