Description

7-Bromo-2,2-dimethyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this precise chemical scaffold to construct complex molecular architectures. Its unique fused pyrido-oxazine structure provides a versatile platform for further functionalization and drug discovery.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of potential drug candidates, especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Potential precursor for the synthesis of specialized organic electronic materials or ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Product Name	7-Bromo-2,2-dimethyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
CAS No.	894852-03-0
Molecular Formula	C9H11BrN2O
Molecular Weight	243.10 g/mol
Synonyms	7-Bromo-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazine; 2H-Pyrido[3,2-b][1,4]oxazine, 7-bromo-3,4-dihydro-2,2-dimethyl-; 894852-03-0; 7-Bromo-2,2-dimethyl-3,4-dihydro-2H-pyrido[3,2-b]-1,4-oxazine; 7-Bromo-2,2-dimethyl-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazine
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,2-dimethyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.