Description

(R)-4-Oxopiperidine-2-Carboxylic Acid CAS NO 894767-26-1 is a high-purity chiral piperidine derivative, serving as a critical building block in modern asymmetric synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex pharmaceutical intermediates and bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure starting materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder drugs.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for metal-catalyzed enantioselective reactions.
• Peptidomimetic Research: Incorporated into novel peptide analogs to modulate biological activity and improve metabolic stability.
• Agrochemical Active Ingredient Development: Serves as a building block for creating new chiral herbicides, fungicides, and insecticides.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes for chiral heterocycles.
• Custom Synthesis & Contract Manufacturing: A requested material for the production of bespoke fine chemicals and advanced intermediates under cGMP or ISO standards.

Basic Information

Product Name	(R)-4-Oxopiperidine-2-Carboxylic Acid
CAS No.	894767-26-1
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	(R)-4-Oxopipecolic Acid; (R)-4-Oxo-2-piperidinecarboxylic Acid; (2R)-4-Oxopiperidine-2-carboxylic Acid; (R)-4-Oxo-piperidine-2-carboxylic Acid; D-4-Oxopipecolic Acid; (R)-4-Oxo-2-piperidinecarboxylic acid; (R)-4-Oxopipecolate; (R)-4-Oxopiperidine-2-Carboxylate
EINECS	Contact for details

Quality Control

Every batch of (R)-4-Oxopiperidine-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) including chiral purity, assay, and impurity profile is supplied with each shipment, supporting compliance with cGMP and ISO 9001 guidelines for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.