Description

2-Trifluoromethyl-Oxazolo[4,5-B]Pyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused oxazolopyridine ring system substituted with a trifluoromethyl group, makes it a critical intermediate for developing novel compounds with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A versatile scaffold for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as ligands for OLEDs or components for organic semiconductors.
• Fluorine Chemistry & Catalysis: An important substrate in studies exploring new fluorination methodologies and the development of novel catalysts that incorporate fluorine-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	2-Trifluoromethyl-Oxazolo[4,5-B]Pyridine
CAS No.	894406-63-4
Molecular Formula	C8H3F3N2O
Molecular Weight	200.12 g/mol
Synonyms	2-(Trifluoromethyl)oxazolo[4,5-b]pyridine; Oxazolo[4,5-b]pyridine, 2-(trifluoromethyl)-; 2-Trifluoromethyloxazolopyridine; 2-CF3-Oxazolo[4,5-b]Pyridine; 2-Trifluoromethyl-1,3-oxazolo[4,5-b]pyridine; TFMP-Oxazolopyridine; 894406-63-4 (CAS Name)
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Oxazolo[4,5-B]Pyridine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support your R&D and scale-up activities. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.