Description

5-(4-Chloro-3-Fluorophenyl)Pyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a halogenated phenyl ring with a pyridine-carboxylic acid moiety, enabling precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A critical starting material for bespoke chemical synthesis services targeting complex, high-value molecules.

Basic Information

Product Name	5-(4-Chloro-3-Fluorophenyl)Pyridine-3-Carboxylic Acid
CAS No.	893740-56-2
Molecular Formula	C12H7ClFNO2
Molecular Weight	251.64 g/mol
Synonyms	5-(4-Chloro-3-fluorophenyl)nicotinic acid; 3-Pyridinecarboxylic acid, 5-(4-chloro-3-fluorophenyl)-; 5-(4-Chloro-3-fluorophenyl)pyridine-3-carboxylic acid; 893740-56-2; 4-Chloro-3-fluorophenyl pyridine carboxylic acid; 5-(4-Chloro-3-fluoro-phenyl)-nicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Chloro-3-Fluorophenyl)Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.