Description

Methyl 5-(2-(Trifluoromethyl)Phenyl)Pyridine-3-Carboxylate is a high-value trifluoromethylated pyridine derivative, a key building block in modern synthetic chemistry. Its core value lies in its unique molecular architecture, which combines a pyridine core with a phenyl-trifluoromethyl moiety, making it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a key scaffold for developing new generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Material Science: Used in the research and development of advanced organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Synthesis: Acts as a versatile building block for further functionalization via hydrolysis, amidation, or cross-coupling reactions to create diverse chemical libraries.
• Ligand & Catalyst Development: Employed in the design of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 5-(2-(Trifluoromethyl)Phenyl)Pyridine-3-Carboxylate
CAS No.	893740-12-0
Molecular Formula	C14H10F3NO2
Molecular Weight	281.23 g/mol
Synonyms	3-Pyridinecarboxylic acid, 5-[2-(trifluoromethyl)phenyl]-, methyl ester; Methyl 5-[2-(trifluoromethyl)phenyl]nicotinate; 5-(2-(Trifluoromethyl)phenyl)nicotinic acid methyl ester; 893740-12-0; Methyl 5-(α,α,α-trifluoro-o-tolyl)nicotinate; 3-Carbomethoxy-5-(2-trifluoromethylphenyl)pyridine
EINECS	Contact for details

Quality Control

Our Methyl 5-(2-(Trifluoromethyl)Phenyl)Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.