Description

5-[4-(Trifluoromethyl)Phenyl]-2-Pyridinamine is a high-value, fluorinated aromatic amine building block, prized for its unique trifluoromethylphenyl-pyridinamine scaffold. This compound is critical for introducing specific steric, electronic, and lipophilic properties into target molecules, directly impacting their biological activity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of small molecule drugs, particularly for kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances compound efficacy and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis or for creating novel organic electronic materials and liquid crystals.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes and activity-based protein profiling (ABPP) agents to study enzyme function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for clinical trial materials.

Basic Information

Product Name	5-[4-(Trifluoromethyl)Phenyl]-2-Pyridinamine
CAS No.	893738-30-2
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]pyridin-2-amine; 2-Amino-5-[4-(trifluoromethyl)phenyl]pyridine; 5-(4-Trifluoromethylphenyl)-2-aminopyridine; 5-(4-Trifluoromethylphenyl)pyridin-2-amine; 2-Pyridinamine, 5-[4-(trifluoromethyl)phenyl]-; α,α,α-Trifluoro-4-(2-amino-5-pyridinyl)toluene
EINECS	Contact for details

Quality Control

Our 5-[4-(Trifluoromethyl)Phenyl]-2-Pyridinamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with each shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.