Description

Methyl 5-(4-Chloro-3-Fluorophenyl)Pyridine-3-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique halogenated pyridine core enables the creation of novel active ingredients. It is primarily sought by process chemists and R&D teams developing new drug candidates, crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand & Catalyst Development: Serves as a sophisticated building block for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in exploratory chemistry for discovering new chemical entities and reaction methodologies.

Basic Information

Product Name	Methyl 5-(4-Chloro-3-Fluorophenyl)Pyridine-3-Carboxylate
CAS No.	893734-89-9
Molecular Formula	C13H9ClFNO2
Molecular Weight	265.67 g/mol
Synonyms	5-(4-Chloro-3-fluorophenyl)nicotinic acid methyl ester; Methyl 5-(4-chloro-3-fluorophenyl)nicotinate; 3-Pyridinecarboxylic acid, 5-(4-chloro-3-fluorophenyl)-, methyl ester; 893734-89-9; Methyl 5-(4-Chloro-3-Fluorophenyl)-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(4-Chloro-3-Fluorophenyl)Pyridine-3-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the exacting standards required for pharmaceutical and advanced agrochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.