Description

4-(Bromomethyl)-3-Methoxy-1,5-Naphthyridine is a high-value brominated naphthyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for lead optimization and scale-up.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active naphthyridine-based molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the naphthyridine scaffold.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of advanced organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Utilized to create tagged or modified molecules for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromomethyl group is a reactive handle for further functionalization via Suzuki, Sonogashira, or Buchwald-Hartwig amination reactions.
• Academic & Contract Research: Fundamental research reagent in universities and CROs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-(Bromomethyl)-3-Methoxy-1,5-Naphthyridine
CAS No.	893566-34-2
Molecular Formula	C10H9BrN2O
Molecular Weight	253.10 g/mol
Synonyms	3-Methoxy-4-(bromomethyl)-1,5-naphthyridine; 1,5-Naphthyridine, 4-(bromomethyl)-3-methoxy-; 4-Bromomethyl-3-methoxy-1,5-naphthyridine; 3-Methoxy-4-(bromomethyl)-1,5-naphthyridine; 893566-34-2; 4-(Bromomethyl)-3-methoxy-[1,5]naphthyridine
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)-3-Methoxy-1,5-Naphthyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard offering meets high-purity research-grade specifications, with comprehensive characterization via HPLC, NMR, and MS. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer requirements or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.