Description

n-[2-Chloro-3-Formyl-4-Pyridinyl]Carbamic Acid tert-Butyl Ester is a high-value, multi-functional pyridine derivative and a key protected intermediate in advanced organic synthesis. Its molecular architecture, featuring both a chloro and a formyl group on the pyridine ring, makes it a versatile building block for constructing complex nitrogen-containing heterocycles. This compound is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used as a building block for developing advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	n-[2-Chloro-3-Formyl-4-Pyridinyl]Carbamic Acid tert-Butyl Ester
CAS No.	893423-62-6
Molecular Formula	C11H13ClN2O3
Molecular Weight	256.69 g/mol
Synonyms	tert-Butyl (2-chloro-3-formylpyridin-4-yl)carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-chloro-3-pyridinecarboxaldehyde; 2-Chloro-3-formyl-4-pyridinylcarbamic Acid tert-Butyl Ester; BOC-Protected 2-Chloro-3-formyl-4-aminopyridine; (2-Chloro-3-formyl-4-pyridinyl)-N-BOC-amine; N-Boc-2-chloro-3-formyl-4-aminopyridine; 4-(Boc-amino)-2-chloro-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our n-[2-Chloro-3-Formyl-4-Pyridinyl]Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques (HPLC, GC, NMR). Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for critical development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.