Description

N,n-Dimethyl-2-((5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Ethanamine is a high-value, advanced pharmaceutical intermediate featuring a pyridine core and a protected boronic ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients, including kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for small molecule drugs targeting various diseases.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between its boronic ester group and aryl/vinyl halides, essential for constructing complex biaryl structures in drug discovery.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probe Synthesis: Utilized to create labeled molecules or probes for studying biological pathways and protein interactions.
• Contract Research & Development (CRO/CMO): Supplied to service organizations supporting drug discovery and process development projects for global clients.

Basic Information

Product Name	N,n-Dimethyl-2-((5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Ethanamine
CAS No.	892501-92-7
Molecular Formula	C15H25BN2O3
Molecular Weight	292.19 g/mol
Synonyms	2-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)-N,N-dimethylethanamine; 2-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]oxy-N,N-dimethylethanamine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-(dimethylamino)ethoxy)pyridine; N,N-Dimethyl-2-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)ethan-1-amine; Pinacol [6-[2-(dimethylamino)ethoxy]-3-pyridyl]boronate
EINECS	Contact for details

Quality Control

Our production of N,n-Dimethyl-2-((5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Ethanamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is characterized by advanced analytical techniques including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.