Description

4-Piperidinecarboxylic Acid T-Butyl Ester Hcl is a high-purity, protected piperidine derivative used as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable, high-quality intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for creating novel peptide-like molecules with enhanced metabolic stability.
• Agrochemical Development: Employed in the research and synthesis of advanced crop protection agents and pesticides.
• Ligand and Catalyst Preparation: Useful for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in academic and corporate research settings.

Basic Information

Product Name	4-Piperidinecarboxylic Acid T-Butyl Ester Hcl
CAS No.	892493-65-1
Molecular Formula	C10H20ClNO2
Molecular Weight	221.72 g/mol
Synonyms	tert-Butyl 4-piperidinecarboxylate hydrochloride; 1-Boc-4-piperidinecarboxylic acid hydrochloride; 4-(tert-Butoxycarbonyl)piperidine-1-carboxylic acid hydrochloride; 1-Boc-piperidine-4-carboxylic acid HCl; Piperidine-4-carboxylic acid tert-butyl ester hydrochloride; 4-Carboxypiperidine tert-butyl ester HCl; Boc-4-piperidinecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxylic Acid T-Butyl Ester Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.