Description

tert-Butyl 1-(5-Aminopyridin-2-yl)piperidine-4-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with both amino and tert-butyl ester functionalities. This compound is of significant value for medicinal chemistry research and development, offering a versatile building block for constructing complex molecular architectures. It is primarily sought after by pharmaceutical companies and contract research organizations engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Used in the research and development of Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Chemical Research: Serves as a versatile scaffold in academic and industrial research for exploring new chemical entities and structure-activity relationships (SAR).
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for pharmaceutical clients.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	tert-Butyl 1-(5-Aminopyridin-2-yl)piperidine-4-carboxylate
CAS No.	892492-27-2
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	1-(5-Aminopyridin-2-yl)piperidine-4-carboxylic acid tert-butyl ester; tert-Butyl 1-(5-amino-2-pyridyl)piperidine-4-carboxylate; 4-Piperidinecarboxylic acid, 1-(5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester; 892492-27-2; 1-(5-Amino-2-pyridinyl)piperidine-4-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(5-Aminopyridin-2-yl)piperidine-4-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.