Description

1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-4-Nitro-3-(Trifluoromethyl)-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]- is a high-value, multi-functionalized heterocyclic building block designed for advanced synthetic chemistry. This compound is engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique scaffold enables the exploration of new chemical space. It is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and specialty chemical industries seeking to create next-generation products with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Process Chemistry: Utilized in route scouting and optimization for scalable manufacturing of fine chemicals.
• Academic & Contract Research: A valuable reagent for methodological studies and novel heterocycle synthesis in academic and CRO laboratories.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-4-Nitro-3-(Trifluoromethyl)-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]-
CAS No.	892414-51-6
Molecular Formula	C14H15ClF3N3O3Si
Molecular Weight	393.82 g/mol
Synonyms	6-Chloro-4-nitro-3-(trifluoromethyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine; 1-((2-(Trimethylsilyl)ethoxy)methyl)-6-chloro-4-nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-4-nitro-3-(trifluoromethyl)-1-[[2-(trimethylsilyl)ethoxy]methyl]-; 892414-51-6; 6-Chloro-4-nitro-3-trifluoromethyl-1-((2-trimethylsilylethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine; SEM-protected 6-chloro-4-nitro-3-(trifluoromethyl)-7-azaindole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch. Our quality management system is designed to meet the stringent requirements of cGMP and ISO guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.